Page 179 - CW E-Magazine (5-12-2023)

CPHI Barcelona 2023

IFF features new excipient formulations

IFF’s Pharma Solutions division put
the spotlight on its leading excipient
products at the CPHI Barcelona.

“We are delighted to announce the
expansion of our portfolio to include
low nitrite excipient solutions and bio-
polymer innovations. IFF continues
to invest in product innovation, capa-
city, and digital capabilities to meet the
evolving needs of the pharmaceutical
industry,” commented Ms. Angela
Strzelecki, President, Pharma Solu-
tions, IFF.

At the show, IFF presented its Avicel
PH LN portfolio – a nitrite microcrys-
talline cellulose (MCC) that lowers
the risk of nitrosamine formation in
finished drug products, catering to the
needs of pharmaceutical customers
seeking excipients to support their nitros-
amine risk mitigation plans. The
solution offers a range of benefits, in- family of water-soluble cellulose use in cell culture media – enabling cell
cluding nitrite specification on certifi- ethers. IFF also launched Methonova, therapies for many advanced diseases –
cates of analysis and batch-to-batch a cell-compatible and filterable methyl- and 3D bioprinting, allowing for
consistency regarding nitrite content. cellulose for the biotechnology indus- example, in-vitro drug testing models
Another highlight was the Methocel tries. This biopolymer is suitable for or 3D cell cultures.

HIGH PURITY INGREDIENTS
Clariant’s new excipients improve stability and

solubility of APIs

Clariant, the Swiss speciality chemi- ionic solubiliser, emulsifying agent of Meglumine. It is used as a coun-
cals company, announced new addi- and stabiliser used in applica- terion in contrast media sector, as
tions to its portfolio of pharmaceutical tions where highest purity require- buffering agent/alkaliser and solu-
ingredient solutions. The company un- ments are demanded to improve the biliser for mild acidic APIs. Appli-
veiled three new VitiPure excipients stability and colour of end formulations. cations include oral solid and liquid
allowing for a multitude of formula- VitiPure CO 35 Superior: a Poly- formulations. It is suitable for for-
tions and administration routes, even oxyl 35 castor oil with low residual mulations where low bioburden and
for sensitive ones, such as mRNA impurities and typically used in par- low endotoxin grade is desired.
vaccines and biologic medications: enteral application where the end
formulation should be colourless, “We’ve built on our proven track-
VitiPure O 80 Superior: a low and the API is sensitive to impuri- record in supporting pharmaceuticals’
microbial load Polysorbate 80, with ties from the excipient. production to create a new Health Care
low residual impurities, offering VitiPure Meglumine LEX: a low- Business Line with a broader portfolio

high stability to APIs. It is a non- endotoxin and microbial-load grade of solutions for the industry’s develop-

Chemical Weekly December 5, 2023 179

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