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Special Report                                                                                                                                                                   Special Report



       Supply chains: Trends in chemical distribution                                                                a review of 600 active substances taken  discussions  in the  Alliance, which  Fine Chemicals Group (EFCG), sup-
                                                                                                                                                       will help the European Commission to  ports potential policy moves to advance
                                                                                                                     from six national lists of critical medi-
                                                                                                                     cines. The goal is update that list on an  identify what it terms as “pipeline  fi ne chemical manufacturing in the EU.
             istributors of chemicals, pharma   (Independent Commodity Intelligence   PATRICIA VAN ARNUM             annual basis.                     investment projects,” which could bene-
             ingredients, and other mate-  Services) identifies Germany-based   Editorial Director                                                     fi t  from  EU  and  national  funding  to   Cefi c’s EFCG issued a set of recom-
       Drials used in bio/pharma         Brenntag as the top distributor with   DCAT                                    The European Commission carried  strengthen manufacturing  in the EU.  mendations last November (Novem-
       development  and manufacturing play   $18.6-bn in 2023 sales, followed by                                     out an analysis of supply-chain vulner-  The Alliance will also look at how mar-  ber 2023), which included fostering
       a crucial role. With increased product   US-based Univar Solutions at $11.5-bn,  cines. Earlier this year (April 2024), the   abilities for a fi rst tranche of 11 critical  ket incentives, such as capacity reser-  supportive legislative policies for  EU
       and supply chain complexity, DCAT   US-based  Tricon Energy at $10.6-bn,  European Commission launched  the   medicines on the Union list, published  vation contracts and joint procurement,  API  manufacturers that emphasized
       Value Chain Insights examines the key   Japan-based Nagase & Co. at $6.5-bn,  Critical Medicines  Alliance. First   in April 2024. The outcome of this work  can be used to enhance security of sup-  sustainable growth and reshoring initia-
       trends and issues impacting  markets   and Netherlands-based IMCD at $5.1-bn.  announced by the European Commission   will inform the scope of the mandate of  ply of critical  medicines.  In addition,  tives while investing in innovation and
       and supply chains.                The regional leaders are Brenntag  in October 2023, the Alliance will focus   the Critical Medicines Alliance. In addi-  the Alliance is taking a holistic  view  shifting procurement focus on supply
                                         (Europe), Univar Solutions (North  on  industrial policy and complements    tion, the European Commission will  of the supply chain, and its members  security and social-environmental stan-
       Market size and top chemical      America), Nagase & Co. (Asia Pacifi c),  the reform of the EU’s pharmaceutical   proceed with evaluating the remaining  will seek to identify new synergies to  dards. In making those recommenda-
       distributors                      and  Tricon Energy (Latin  America/  legislation as proposed by the European   medicines in the Union list. It will then  work with each other more effectively,  tions, EFCG  pointed to the continued
          Chemical distribution encompasses   Middle East & Africa). The ICIS Top  Commission. Set up as a consultative   recommend priority actions for the near  including creating new  partnerships.  decline  of European-based  API pro-
       a wide scope of products, markets, and   100  Chemical Distributors ranking is  mechanism  to  policy-makers,  the   future and propose new tools to address  Given the global nature of the supply  duction  with respect  to the  supply of
       industries. Essential raw  materials are   based on 2023 sales and year-end 2023  Alliance seeks to work to enhance secu-  the challenges it has identifi ed. In partic-  chain, these new  partnerships could  critical medicines. From a global pro-
       produced and supplied by the chemical   currency exchange rates.   rity of supply, strengthen availability    ular, the recommendations will focus on  bring the diversifi cation of the supply  duction share of 53% in 2000, the EU’s
       industry  to  businesses in  manufactur-                           of medicines, and reduce EU supply-        mitigating  structural risks, reinforcing  chain of critical medicines.  share of API production in 2020 fell to
       ing and industrial sectors.  These raw   The ICIS Top 100 Chemical Distri-  chain dependencies. The recommenda-  supply by making demand more                                     25% due to increased competition from
       materials  are  either  sold directly  by   butors was compiled with the support of  tions made by the Alliance will serve as   predictable, encouraging diversifi-  The European  Chemical  Industry  lower-cost countries and EU pricing
       producers or distributed to end users   several industry associations represent-  a basis for a multi-year strategic  plan   cation, and boosting manufacturing in  Council  (Cefi c),  which  represents  EU  and procurement policies  not favour-
       by outside distributors. Due to the out-  ing chemical distributors: the European  containing milestones and correspond-  the EU.               chemical  manufacturers, is a member  able to  EU-based  domestic manufac-
       sourcing of value-added services, such   Association of Chemical  Distributors,  ing deadlines for their implementation.                        of the Critical Medicines Alliances, and  turing,  according to information  from
       as logistics, packaging, blending, waste   the US-based  Alliance for  Chemical                                  Those efforts will also be part of  through its sector group, the European  EFCG.
       removal, inventory management,  and   Distribution (formerly the National   Key factors being analysed include
       technical  training, the distribution of   Association of Chemical Distributors),  an over-dependency on a limited num-
       commodity and specialty chemicals by   Associquim (the Brazilian  Association  ber of external suppliers, limited diver-             Target Your Market More Effectively
       third parties is predicted to grow more   of Chemical and Petrochemical Distri-  sifi cation possibilities, and limited pro-
       than the sale of products directly to end   butors),  Responsible  Distribution  duction capacities.  This will build on                            IndiaChemTrade
       users, according to a recent analysis by   Canada), UK-based Chemical Business  the European Commission’s vulnerabi-                            Free for subscribers of Chemical Weekly
       Grand View Research, a San Francisco,   Association,  and Netherlands-based  lity analysis of supply-chain bottlenecks
       California-based business  intelligence   International Chemical Trade Associa-  of critical medicines on the Union list   IndiaChemTrade provides consolidated trade statistics of India. The information provided here is based on
       fi rm.                             tion.                            of critical medicines. The Union list of      the annual trade data published by the Directorate General of Commercial Intelligence and Statistics,
                                                                          critical medicines, which was published       Government of India. The database can be searched by: Chemical Name/Harmonised Code to obtain the
          The global chemical  distribution   Pharma ingredient supply lines  by the European Medicines Agency last     consolidated trade (import or export) in that item; or by Country to obtain the trade (import or export) in all
       market was  valued at $256.6-bn  in   Raw materials, chemicals, and  December (December 2023), refers to         chemicals and related products between India and that country.
       2023 and is anticipated  to grow at a   related  inputs used in pharmaceutical  a list of critical medicines for the EU/
       compound annual growth rate of 6.3%   production represent just one segment  European Economic Area, which con-
       from 2024 to 2030, according to Grand   in  the global chemical distribution  tains more than 200 active substances                                   ChemXchange
       View Research. The demand for chemi-  market.  In looking  at  broader  issues  of  medicines considered critical for
       cal distribution is projected to be driven   impacting pharmaceutical supply chains  healthcare  systems across the EU/                          Open to all – no subscription required
       by  rising  chemical  consumption  in  a   and related inputs, a key issue poten-  European Economic  Area, for  which   ChemXchange – the chemical exchange with a difference – is where you can identify your buyers and
       variety of end-use industries, including   tially impacting pharm ingredient sup-  continuity  of supply  is a  priority  and   supplyers on-line, any time. Listing in this unique platform is free to all advertisers in the print version
       pharmaceuticals, construction,  poly-  ply chains in the Europe Union (EU)  for which shortages should be avoided.
       mers & resins, and plastics.      relates to policy moves to increase  The  list contains active  substances of   of Chemical Weekly for a period of 12 months.
                                         manufacturing  in the EU and reduce  innovator  and generic  drugs covering
          In looking at the top global chemi-  dependence on other countries for  a wide range of therapeutic areas and                      For more information contact: 022-24044471 / 72
       cal distributors, in its annual analysis of   active pharmaceutical ingredients (APIs)  includes vaccines and medicines  for   Email: corporate@chemicalweekly.com or log on to chemicalweekly.com
       the top 100 chemical distributor, ICIS   and related  inputs for critical  medi-  rare diseases. It refl ects the outcome of


       178                                                                      Chemical Weekly  July 30, 2024       Chemical Weekly  July 30, 2024                                                                  179


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