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Sapala Organics Private Limited                                                                                   HRISHABH LIFE SCIENCES

                                                            Turning Chemistry into Reality.........                                       www.hrishabhlife.com


            An unique organisation where both excellence in synthetic skills & state-of-the-art                             DIRECT IMPORTER/AUTHORISED REPRESENTATIVE OF BELOW MENTIONED CHEMICAL
            analytical support coexist under single roof offering seamless services to the academic &                 • 1,3-Bromo Chloro Propane   • Di Ethyl Sulphate   • Methane Sulfonyl Chloride   • Phthalic Anhydride
            industrial customers                                                                                      • 1,3-Di Fluoro Benzene  • Di Iso Propyl Ether   • Methane Sulphonic Acid   • Poly Phosphoric Acid
                                                                                                                      • 1,4 Dioxane
                                                                                                                                                                                                 115% / 116% / 118%
                                                                                                                                                                       • Methyl Aceto Acetate
                                                                                                                                             • Di Methyl Acetamide
                                        FOCUS AREAS OF SAPALA                                                         • 1H-1 2 4 Triazole    • Di Methyl Carbonate     • Methyl Acrylate        • Potassium Acetate
                                                                                                                      • 2,4-Di Chloro Acetophenone   • Di Methyl Formamide   • Methyl Chloro Formate    • Potassium Carbonate Granules
                         MEDICINAL CHEMISTRY                      NUCLEOSIDE CHEMISTRY                                • 2-Methyl THF         • Di Methyl Sulfoxide     • Methyl Cyano Acetate   • Potassium Carbonate Powder
                                                                                                                      • 4-Chloro Butyryl Chloride   • Di Methyl Sulphate   • Methyl Iso Butyl Ketone   • Potassium Iodide
               Drug Discovery / Lead Optimisation             Nucleosides & Amidites                                  • 4-Di Methyl Amino Pyridine   • Di Potassium Hydrogen Ortho Phosphate  • Methylene Di Chloride  • Potassium Permanganate
               Scaffold Synthesis                             Carbohydrate & Lipids                                   • 4-Amino 1,2,4-Triazole   • Di tert Butyl Dicarbonate  • Mono Chloro Benzene   • Potassium Tert Butoxide
                                                                                                                                             • Dicyclohexylcarbodiimide
                                                                                                                      • 4-Bromo Anisole
                                                                                                                                                                       • Mono Ethanol Amine
                                                                                                                                                                                                • Propionaldehyde
               Library Molecules                              Fluorescent Dyes                                        • Acetonitrile         • Diglyme                 • Mono Ethylene Glycol   • Propionic Acid
               Synthesis of Reference Standards & Impurities   Linker & Spacers for Oligonucleotides                  • Acetophenone         • DL Tartaric Acid        • Mono Iso Propyl Amine 70% / 99%  • Propylene Glycol
                                                                                                                                                                                                • Pyridine
                                                                                                                                             • Epichlorohydrin
                                                                                                                      • Acrylic Acid
               Process Development for Lead Compounds         Phosphorylation Chemistry (NTP)                         • Acrylonitrile        • Ethyl Acrylate          • Mono Methyl Amine 40%   • R(+)Phenyl Ethyl Amine
                                                                                                                                                                       • Monoglyme
                                          ANALYTICAL SERVICES                                                         • Adipic Acid          • Ethyl Cellosolve Acetate   • Morpholine          • Refined Naphthalene
                                                                                                                      • Allyl Alcohol
                                                                                                                                                                       • N-Butyryl Chloride
                                                                                                                                                                                                • Resorcinol
                                                                                                                                             • Ethyl Chloro Formate
                                                                                                                      • Allyl Chloride       • Ethylene Di Amine       • N-Heptane              • Sodium Acetate
                                                                                   THERMAL STUDIES &
               SPECTROSCOPY          CHROMATOGRAPHY            WET ANALYSIS        SPECIAL EQUIPMENT                  • Alpha Naphthol       • Formamide               • N-Methyl 2-Pyrrolidine  • Sodium Bi Carbonate


                                                                                                                                             • Formic Acid 85%/99%
                                                                                                                      • Aluminium Chloride
                                                                                                                                                                       • N-Butanol
                                                                                                                                                                                                •  Sodium Borohydride Powder / Granules
                                                                                                                      • Ammonium Bicarbonate   • Glycerine             • Nitromethane           • Sodium Carbonate
               NMR - 400 & 500 MHz    HPLC - PDA, UV & RI     Autotitrator            DSC                             • Ammonium Thiocyanate   • Glyoxal 40%           • N-Methyl Piperazine    • Sodium Citrate
               LC-MS/LC-MS-MS         HPLC- ELSD & CAD        Gravimetric analysis    TGA                             • Benzene              • Hydrazine Hydrate 64% / 80% / 100%  • N-Propanol  • Sodium Metal
               UPLC-MS                Prep. HPLC              Argentometric titration  Elemental analysis             • Benzophenone         • Hydrobromic Acid 48%    • N-Propyl Bromide       • Sodium Methoxide Powder
                                                                                                                                             • Hydrogen Peroxide 50%
                                                                                                                      • Benzoyl Chloride
                                                                                                                                                                                                • Sodium Methoxide Solution
                                                                                                                                                                       • Ortho Di Chloro Benzene
               GC-MS                  GC                      Coulometric Karl Fischer  (C, H, N, S, O)               • Benzyl Amine         • Hydroxylamine Hydrochloride  • Ortho Nitro Aniline   • Sodium Nitrite
               FTIR, UV, SOR          GCHS                    Heavy metal ROI         ICP-MS                          • Beta Napthol         • Hydroxylamine Sulphate   • Ortho Phenylene Diamine  • Succinic Acid
                                                                                                                                                                                                • Tert Butylamine
                                                                                                                      • Butyl Acetate
                                                                                                                                             • Imidazole
                                                                                                                                                                       • Ortho Toluic Acid
                                   OLIGONUCLEOTIDES SERVICES                                                          • Caustic Potash Flakes   • Iodine               • Para Anisidine         • Tertiary Butanol
                                                                                                                                                                                                • Tetra Butyl Ammonium Bromide
                                                                                                                      • Caustic Soda Flakes
                                                                                                                                             • Iso Propyl Acetate
                                                                                                                                                                       • Para Hydroxy Benzaldehyde
                                     “All Your String of Beads in One Place”                                          • Caustic Soda Lye     • Isovaleraldehyde        • Para Nitro Chloro Benzene  • Tetrahydrofuran
            With our expertise in Nucleic acid chemistry with more than 15 years of experience, we                    • Chloroform           • L(+)Tartaric Acid       • Para Toluene Sulfonyl Chloride  • Thionyl Chloride
                                                                                                                                                                                                • Thiophenol
                                                                                                                                                                       • Para Toluic Acid
                                                                                                                      •  Citric Acid Monohydrate/Anhydrous • Liquid Bromine
            provide complete package for synthesis, process development and manufacturing of                          • Cyanoacetamide       • L-Proline               • Para Toluic Sulphonic Acid   • Thiourea
            oligonucleotides spanning from phosphoramidite synthesis to oligonucleotides                              • Cyclopropylamine     • Malononitrile           • Paraformaldehyde 91% / 96%  • Tri Ethyl Ortho Formate
                                                                                                                      • Cyclohexane          • Maleic Anhydride        • Petroleum Ether 40-60 / 60-80  • Tri Methyl Borate
                     >50 years of combined experience in oligonucleotide and Phosphoramidite synthesis                • Cyclohexanol         • Malonic Acid            • Phenol                 • Tri Methyl Ortho Acetate
                                                                                                                      • Cyclohexylamine      • Meta Di Chloro Benzene  • Phenyl Chloro Formate   • Tri Methyl Ortho Formate
                                    “Scale of Synthesis from 1μmol to 12 mMol”                                        • D(-)Tartaric Acid    • Meta Xylene             • Phosphorous Oxychloride  • Tri- N- Butyl Amine
                                                                                                                      • Di Ethyl Carbonate   • Methacrylic Acid        • Phosphorous Pentoxide  • Tri Phenyl Phosphine
                                                                                                                      • Di Ethyl Malonate    • Methallyl Chloride      • Phosphorous Trichloride  • Triphosgene
                                Services                                 Modalities
                                                                                                                                 AVAILABLE IN TANKER LOAD BULK SOLVENT - (EX-MUMBAI-KANDLA-HAZIRA
               Exploratory Research (Non-GMP)-Base             Antisense Oligonucleotides (ASO)                                                AND ALSO AVAILABLE IN  DRUMS AT BHIWANDI)
               backbone & sugar modificationst                 SiRNA
               Process development                             Aptamer, miRNA                                          •  Acetic Acid                •  Iso Butanol                    •  Mix Xylene
               Toxicology and Pre-Clinical supply              Conjugated oligos (lipid & GalNAc)                      •  Acetone                    •  Iso Propyl Alcohol             •  N-Butanol
                                                                                                                                                                                       •  Phenol
                                                                                                                       •  Caustic Soda Lye
                                                                                                                                                     •  Methanol
               Analytical method development-Combination       Morpholino Oligos                                       •  Chloroform                 •  Methyl Ethyl Ketone            •  Styrene Monomer
               of orthogonal analytical techniques             Primers, Probes & Fluorescent oligos                    •  Cyclohexanone              •  Methyl Iso Butyl Ketone        •  Toluene
                                          BUSINESS MODELS                                                              •  Ethyl Acetate              •  Methylene Di Chloride          •  Vinyl Acetate Monomer
               FTE-Based Contract Research                     FFS-Custom Synthesis Services                                      Can also offer our supply to SEZ Units against LUT without Payment of IGST
               Contract Development & Manufacturing Organisations-CDMO                                                 HRISHABH LIFE SCIENCES                                    For Enquiry Contact: Ms Pooja . Y
                Sapala Organics Pvt Ltd.                          For any immediate need for                           Unit No:- 1003, 10th Floor, Solaris One,                  Email  : info@hrishabhlife.com
                Plot Nos. 146B & 147, IDA Mallapur, Phase-II,     Analytical servcies                                  N. S. Phadke Marg, Opp. Telli Galli,                      Mobile  : 9820999085 / 9082349465
                Hyderabad,  India -500076.                                                                             Andheri Flyover Bridge,                                   Phone  : 022-66620942 /
                Phone: +91-40-27170174, 75, 76                    Contact on: +91-8978043456 & 9963111467
                Email: info@sapalaorganics.com                    Email: customercare@sapalaorganics.com               Andheri - East, Mumbai - 400 069. INDIA.                           66620943 / 66620944
       58                                                                  Chemical Weekly  December 19, 2023
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